Name :
CSF1R (Human) Recombinant Protein
Biological Activity :
Human CSF1R (NP_005202.2, 543 a.a. – 972 a.a.) partial recombinant fusion protein with GST-His6 tag at N-terminal with a thrombin cleavage site.Bioactive Protein,Bioactive Proteins,Bioactive,Active,Functional Protein,Functional Proteins
Tag :
Result of activity analysis
Protein Accession No. :
NP_005202.2
Protein Accession No.URL :
https://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=1436
Amino Acid Sequence :
Molecular Weight :
77.733
Storage and Stability :
Store at -80°C.Aliquot to avoid repeated freezing and thawing
Host :
insect
Interspecies Antigen Sequence :
Preparation Method :
Insect cell (Sf9) expression system
Purification :
GST affinity chromatography
Quality Control Testing :
2 ug/lane SDS-PAGE Stained with Coomassie Blue
Storage Buffer :
In 50 mM Hepes, 100 mM NaCl, pH 7.5. (5 mM DTT, 15 mM reduced glutathione, 20% glycerol).
Applications :
Functional Study， SDS-PAGE，
Gene Name :
CSF1R
Gene Alias :
C-FMS, CD115, CSFR, FIM2, FMS
Gene Description :
colony stimulating factor 1 receptor
Gene Summary :
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq
Other Designations :
CD115 antigen|FMS proto-oncogene|McDonough feline sarcoma viral (v-fms) oncogene homolog|macrophage colony stimulating factor I receptor|soluble CSF1R variant 1
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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