Mouse LY75/CD205 Protein 3460

Additional Information:
inaccessionQ60767|express systemHEK293|product tagC-His|purity> 95% as determined by Tris-Bis PAGE|backgroundLymphocyte antigen 75 (Ly75/CD205) is a surface marker on mitotic germ cells in rainbow trout. In mammals, several cell surface molecular markers have been characterized in order to identify the mitotic germ cells. he expression profile of Ly75 protein was similar to that of the mRNA. Furthermore, identification of various fish homologs of ly75 confirmed that their amino acid sequences are well conserved. Therefore, Ly75 may be appropriate for use as a versatile cell surface marker for mitotic germ cells in fish.|molecular weightThe protein has a predicted MW of 189.5 kDa. Due to glycosylation, the protein migrates to 235-250 kDa based on Tris-Bis PAGE result.|available size100 g, 500 g|endotoxinLess than 1EU per g by the LAL method.|Mouse LY75/CD205 Protein 3460proteinSize and concentration100, 500g and lyophilizedFormLyophilizedStorage InstructionsValid for 12 months from date of receipt when stored at -80C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.Storage bufferShipped at ambient temperature.Purity> 95% as determined by Tris-Bis PAGEtarget relevanceLymphocyte antigen 75 (Ly75/CD205) is a surface marker on mitotic germ cells in rainbow trout. In mammals, several cell surface molecular markers have been characterized in order to identify the mitotic germ cells. he expression profile of Ly75 protein was similar to that of the mRNA. Furthermore, identification of various fish homologs of ly75 confirmed that their amino acid sequences are well conserved. Therefore, Ly75 may be appropriate for use as a versatile cell surface marker for mitotic germ cells in fish.Protein namesLymphocyte antigen 75 (Ly-75) (DEC-205) (CD antigen CD205)Gene namesLy75,Ly75 CD205Mass10090DaFunctionActs as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Causes reduced proliferation of B lymphocytes (By similarity).Subellular locationMembrane ; Single-pass type I membrane protein .TissuesExpressed in dendritic and thymic epithelial cells and lymph nodes.Post-translational modificationN-glycosylated.Target Relevance information above includes information from UniProt accession: Q60767The UniProt Consortium|