Using different approaches such as the synthesis of structural analogues
Combining these insights into an analysis of structure/activity relationships, we revealed that both the...
The rearrangement of cytoskeletal elements a phenomenon associated
In follow-up studies, long term GRN163L exposure could limit the lifespan of cultivated MEDChem...
It was recently reported that SLAMF3 has a similar role in lymphocytes
as QSI than aromatic or polyaromatic compounds. Indeed, solenopsin A, a venom alkaloid produced...
In HCC the observed genetic alterations lead to an imbalance in the antiapoptotic
antioxidants and renin-angiotensin system inhibitors have met with limited success due, not only, to...
A promising candidate for an anti-DENV drug in the Walker
HIPKs in general and HIPK2 in particular, and they highlight the striking superiority of...
NS3 ATPase and helicase activities by performing a dose response analysis
study for patients with locally advanced rectal cancer given neoadjuvant chemoradiotherapy were approved by...
Clinical use as drugs for a number of diseases are associated
Using a technique pioneered by Pelham and Wang and refined by others, the role...
Here we highlight the importance of human cell-based functional assays to investigate drug efficiency
translation of cap-dependent mRNAs encoding cell cycle regulators and anti-apoptotic proteins. Eukaryotic initiation factor...
The lack of activity displayed by the other four compounds is likely to be attributed
These MMPs are released by local cells as well as by infiltrating leukocytes and...
With the negatively charged residues lining the sub-pockets of the hPC6 active
However, the number of potent and selective inhibitors remains small and the community still...