Product Name :
Zenarestat
Description:
Zenarestat is a potent and orally active aldose reductase inhibitor. Zenarestat improves diabetic peripheral neuropathy in Zucker diabetic fatty rats.
CAS:
112733-06-9
Molecular Weight:
441.64
Formula:
C17H11BrClFN2O4
Chemical Name:
2-{3-[(4-bromo-2-fluorophenyl)methyl]-7-chloro-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl}acetic acid
Smiles :
OC(=O)CN1C2=CC(Cl)=CC=C2C(=O)N(CC2=CC=C(Br)C=C2F)C1=O
InChiKey:
SXONDGSPUVNZLO-UHFFFAOYSA-N
InChi :
InChI=1S/C17H11BrClFN2O4/c18-10-2-1-9(13(20)5-10)7-22-16(25)12-4-3-11(19)6-14(12)21(17(22)26)8-15(23)24/h1-6H,7-8H2,(H,23,24)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Enfortumab (anti-Nectin-4)} medchemexpress|{Enfortumab (anti-Nectin-4)} Nectin-4|{Enfortumab (anti-Nectin-4)} Protocol|{Enfortumab (anti-Nectin-4)} Purity|{Enfortumab (anti-Nectin-4)} supplier|{Enfortumab (anti-Nectin-4)} Autophagy}
Additional information:
Zenarestat is a potent and orally active aldose reductase inhibitor.{{Liarozole} web|{Liarozole} Metabolic Enzyme/Protease|{Liarozole} Immunology/Inflammation|{Liarozole} Biological Activity|{Liarozole} Description|{Liarozole} manufacturer} Zenarestat improves diabetic peripheral neuropathy in Zucker diabetic fatty rats.PMID:33228462 |Product information|CAS Number: 112733-06-9|Molecular Weight: 441.64|Formula: C17H11BrClFN2O4|Chemical Name: 2-{3-[(4-bromo-2-fluorophenyl)methyl]-7-chloro-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl}acetic acid|Smiles: OC(=O)CN1C2=CC(Cl)=CC=C2C(=O)N(CC2=CC=C(Br)C=C2F)C1=O|InChiKey: SXONDGSPUVNZLO-UHFFFAOYSA-N|InChi: InChI=1S/C17H11BrClFN2O4/c18-10-2-1-9(13(20)5-10)7-22-16(25)12-4-3-11(19)6-14(12)21(17(22)26)8-15(23)24/h1-6H,7-8H2,(H,23,24)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Zenarestat (3.2, 32 mg/kg; p.o.; daily for 8 weeks) inhibits nerve sorbitol accumulation in a dose-dependent manner.|Products are for research use only. Not for human use.|
