(2S,3S,5S)-2-(1,3-Benzodioxol-5-yl)-3,5-dihydro-5-methoxy-3-methyl-5-(2-propen-1-yl)-6(2H)-benzofuranone | CAS Number: 57430-03-2

Product: Elacestrant (dihydrochloride)

Product Name
(2S,3S,5S)-2-(1,3-Benzodioxol-5-yl)-3,5-dihydro-5-methoxy-3-methyl-5-(2-propen-1-yl)-6(2H)-benzofuranone
CAS Number
57430-03-2

Synonyms
(2S)-2α-(1,3-Benzodioxol-5-yl)-3,5-dihydro-5α-methoxy-3β-methyl-5-allyl-2H-benzofuran-6-one; (2S,3S,5S)-2-(1,3-Benzodioxol-5-yl)-3,5-dihydro-5-methoxy-3-methyl-5-(2-propen-1-yl)-6(2H)-benzofuranone

Item No.
ALB-RS-2945
Purity
95%

Molecular Formula
C20H20O5
Molecular Weight
340.37

Certification | Grade
NMR | HPLC
Supplier
ALB Technology Limited

COA

MSDS

Chemical Structure

PMID: 2889795

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5-lipoxygenase activating protein Polyclonal Antibody

BMS-1001 hydrochloride

AKAP13 Polyclonal Antibody

Cav 2.2 blocker 1

4-Nitrofurazone metabolite Monoclonal Antibody (6)

Benfluorex hydrochloride

AFAP Monoclonal Antibody (OTI2A3)

NAE-IN-M22

m-PEG25-NHS ester

SHP099 hydrochloride

ACT-132577

CPI-169

XBP-1 polyclonal antibody

Remodelin hydrobromide

TLR7 monoclonal antibody (4F4)

Neochlorogenic acid

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Aloperine

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PCR decontamination kit

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Dehydrocorydaline nitrate

Nitric oxide synthase (endothelial) polyclonal antibody

NGAL (pig) monoclonal antibody (17)

Neomycin ELISA kit

Isoliquiritin apioside

Hydroxytyrosol-d4

MMP-2 (catalytic domain) (human), (recombinant)

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5Z-7-Oxozeaenol

L-Theanine

IL-1β (human), ELISA kit

Zenarestat

AG-825

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HKGreen-4I

Isoescin IA

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Quinupristin

Glycitin

D-(+)-Galacturonic acid sodium salt

Sapropterin dihydrochloride

7-Methoxy-4-methylcoumarin

4,4′-Diazido-2,2′-stilbenedisulfonic acid disodium salt tetrahydrate

MD2-TLR4-IN-1

Daucosterol

2-Hydroxy-4-methylbenzaldehyde

StayGold Nanoselector Agarose

N-(m-PEG4)-N’-(azide-PEG4)-Cy3

ESI-08

L-Leucine

Isotyping Kit for Mouse Monoclonal Antibody

CH2COOH-PEG3-CH2COOH

Anti-SIGLEC3/CD33(Lintuzumab Biosimilar) Antibody

Anti-MS4A1/CD20(Obinutuzumab Biosimilar) Antibody

Emodin-d4

Anti-AXL(Mecbotamab Biosimilar) Antibody

Anti-Microcystis aeruginosa Microcystin-LR, AlpSdAbs® VHH

BMS-587101

4-Hydroxyphenylbutazone

Anti-Human NAP1L1, AlpSdAbs® VHH

Anti-Chick LYZ/Lysozyme C, AlpSdAbs® VHH

STOCK2S-26016

(5R, 6E)-5-Hydroxy-1, 7-diphenyl-6-hepten-3-one

Anti-Biotin, Rabbit antibody(iFluor488)

Anti-IL13RA1, Human antibody

Ursolic acid acetate

Demoxepam

Guggulsterone E&Z

Ertugliflozin

(-)-Epigallocatechin-3-(3”-O-methyl) gallate

Itaconate-alkyne

Clotrimazole

CDN1163

25-O-Methylalisol A

Mal-amido-PEG3-C1-PFP ester

TT01001

CPDA inhibitor

SS28

Miglustat

XL413 Hydrochloride(x)

Imatinib hydrochloride

TP 003

NNC 63-0532

5-Nonyloxytryptamine oxalate

Ac-RYYRIK-NH2

Rilmazafone hydrochloride

DEHP

Nithiamide

Argininic acid

Royal Jelly acid

SR-4370

Sulfosuccinimidyl oleate sodium

HEAT hydrochloride

SSR128129E (free acid)

AZD2932

SB-269970 Hydrochloride

Sumatriptan succinate

Ranolazine

SPL-410

5′-O-DMT-N2-ibu-dG

HCGRP-(8-37)

Syringetin-3-O-rutinoside

Taltirelin acetate

GZD824 dimesylate

Teneligliptin hydrobromide hydrate

(1R)-α-Pinene

Bisabolone oxide A

Methyl mycophenolate

Terbutaline sulfate

PHA-680632

Gabapentin(Neurontin)

(R)-(-)-Rolipram

Cinepazide Maleate

SNIPER(CRABP)-11

PD-161570

CNQX disodium

GSK-3117391

NVP-TNKS656, Wnt / Tankyrase Inhibitor

OICR9429 — WDR5 Antagonist

OSI-027 — mTOR Inhibitor

RO4929097 — γ-Secretase Inhibitor

(R)-Lanicemine

Trimetazidine-N-oxide

Thiocolchicine

Tezacitabine

8-Methyl Chrysophanol

Benzyl-PEG7-amine

Benzyl-PEG4-Ots

Ardisiacrispin A

Lanreotide acetate

Hydroxy ipronidazole

S3QEL-2

(2S, 4S)-4-(Acetylthio)-2-[(dimethylamino)carbonyl]-1-pyrrolidinecarboxylic Acid 4-Nitrobenzyl Ester-d6

Voglibose

Bucolome — CYP2C9 inhibitor

10β, 17β-dihydroxyestra-1, 4-dien-3-one

Ethyl oleate

Ocinaplon

Bucindolol

(S, R, S)-AHPC-C8-NH2 hydrochloride

m-PEG15-alcohol

Ziprasidone

BMS-911543

Dezapelisib

HIV-1 inhibitor-9

PF-03715455

Setogepram

4-Nitrophenyl α-D-galactopyranoside

HS-PEG7-CH2CH2N3

6-Bromohexylphosphonic acid

Azvudine hydrochloride

Dicaprylyl carbonate

Wistin

Histone H3 (21-44)

Draflazine

AMG 487

Oteseconazole

Fmoc-NH-PEG11-CH2COOH

PC-Biotin-PEG4-NHS carbonate

Lobeline sulfate

FGIN-1-27

Ro 106-9920

(3S, 5S)-Atorvastatin (sodium salt)

ATB-343

Pimelic acid, 98%

1-Indanone, 99+%

Thiophene-3-carboxylic acid, 99%

Platinum, nominally 50%, Ruthenium nominally 25% on high surface area advanced carbon support

2-Chloro-5-(chloromethyl)pyridine, 96%

(3,5-Dichlorophenyl)methanesulfonyl chloride, 97%

1H-Benzimidazole-4-carboxylic acid, 97%

2-Bromo-4,6-dimethylaniline, 98%

o-Tolylacetonitrile, 98+%

2-Thienylzinc bromide, 0.5M in THF, packaged under Argon in resealable ChemSeal™ bottles

Potassium methanesulfonate, 99%

2,5-Dimethoxyterephthalaldehyde, 97%

Methyl diphenylphosphinite, 98+%

Ethyl trans-2-amino-1-cyclohexanecarboxylate hydrochloride, 98%

Indium foil, 0.05mm (0.002in) thick, 99.99% (metals basis)

Aluminum slug, 6.35mm (0.25 in.) dia. x 12.7mm (0.50 in.) length, Puratronic™, 99.999% (metals basis)

2-Methylimidazo[4,5-c]pyridine, 96%

2-Amino-6-methylbenzoic acid, 98%

Triethylene glycol, 99%

Potassium hydrogen phthalate, 99+%

1,3-Dibromo-2,2-dimethoxypropane, 98%

D-(+)-Glucose monohydrate

(-)-Diethyl D-tartrate, 99%, made from unnatural tartaric acid

Tartronic acid, 97%

Decanoyl chloride, 98%

Diphenyl Phosphite, Contains Varying Amounts of Phenol and (C6H5O)3P

Silicon(IV) oxide, 30% in Ethylene glycol, colloidal dispersion

Sodium 2-ethylhexanoate, 97%

Potassium hexacyanoferrate(III), 98+%

Sulfur in Diesel Fuel standard solution, Specpure™, 20,000μg/g (2.00%)

5-Isopropyl-2-methoxybenzaldehyde, 97%

Alizarin Red S sodium salt

1-Bromo-2,4-dimethoxybenzene, 98%

2,2-Dimethoxy-2-phenylacetophenone, 99%

TE Buffer, 1X Solution pH 8.0, Low EDTA, Molecular Biology Grade

Allylthiourea, 98%

D-Fructose 1,6-bisphosphate trisodium salt octahydrate, 98%

6-Fluoroindole, 98%

Potassium iodide, 99.99% (metals basis)

Pyrogallol, 99%

Tetra-n-heptylammonium bromide, 99%

2-Heptanone, 98%

Sodium carbonate, 99.6%, ACS reagent, anhydrous

Pyridine-d{5}, 99.5% (Isotopic), contains 0.05% v/v TMS

Acenaphthenequinone, 95%

Acetone-d6, for NMR, packaged in 0.75ml ampoules, 100.0 atom % D

4-Benzoyl-3-methyl-1-phenyl-5-pyrazolinone, 98+%

D-alpha-Tocopherylquinone, 90-95%

O-(Trimethylsilyl)hydroxylamine, 97%

Bafilomycin A1

Tetrahydrofuran, Biograde, 99.8%, unstab.

Chromium selenide, Black powder, 99.5% (Metals basis)

Vitamin A palmitate, 1.7 M.I.U./g

1-Bromopropane, 99%

3-Mercapto-1-hexanol, 96%

Chlorobenzene, 99+%, for spectroscopy

Germanium(IV) bromide, 99.999% (metals basis)

Sodium D-glucuronate monohydrate, 99%

Silver nanopowder, APS 20-40nm, 99.9% (metals basis)

4-Bromobenzenediazonium tetrafluoroborate, 96%

1,5-Dichloropentane, 98%

1-Aminohydantoin hydrochloride, 98%

Tin shot, 8-20 mesh, 99.8% (metals basis)

Bis(4-fluorophenyl) disulfide, 98%

6,7-Dihydroxy-4-methylcoumarin, 97%

2,5-Pyrazinedicarboxylic acid dihydrate, 97%

Dimethylphosphinic chloride, 97+%

N,1-Di-Boc-L-histidine dicyclohexylammonium salt, 98%

5-Phenylcyclohexane-1,3-dione, 97%

Piperacillin, 95%

1,3-Cyclohexanediol, cis + trans, 98%

Sodium hydrogen carbonate, 99%

N,N,2,4,6-Pentamethylaniline, 98%

4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, 97%

4-Nitrobenzhydrazide, 98+%

1-n-Hexyl-3-methylimidazolium iodide, 98%

(S)-(-)-2-Methyl-2-propanesulfinamide, 97%

6-Bromohexanenitrile, 97%

Tetrahydrofuran, non-UV, HPLC Grade, 99.7+%, stab. with 250ppm BHT

Barium ethoxide, 99.5% (metals basis), 10% w/v in ethanol

Phenyltrimethylammonium tribromide, 97%

Al-23 Fish Spine Beads;OD (mm), 4.0;Bore (mm), 1.5;Length (mm), 4.7

4,5,6-Triaminopyrimidine sulfate hydrate, 98+% (dry wt.), water <8%

Zirconium(IV) oxide, cement

2-Bromo-4-fluoropyridine, 97%

2-Fluoro-N-methylbenzamide, 97%

3-Methyl-1-butanol, mixture of isomers, 99%

8-Bromooctanoic acid, 95%

N,N-Dimethylformamide diethyl acetal, 95%

Boron powder (96+ atomic % B-11), crystalline, 40-230 mesh, 99.9% (metals basis)

4-(4-Hydroxy-3-methoxyphenyl)-2-butanone, 97%

2-Amino-3-picoline, 96%

Absolute Ethanol, 200 proof, Molecular Biology Grade

Sulfuric acid, 0.05N Standardized Solution

(S)-1,2,3,4-Tetrahydro-1-naphthoic acid, 98%

Isobutyl acetate, 98%

Ammonium sulfate, 99%, pure

Nickel slug, 3.175mm (0.125in) dia x 6.35mm (0.25in) length, Puratronic™, 99.995% (metals basis)

Dihydrogen hexachloroplatinate(IV) hydrate, 99.9% (metals basis)

Blue Tetrazolium chloride

4-Acetoxycinnamic acid, predominantly trans, 98+%

4-Methylumbelliferyl-beta-D-xylopyranoside, 99%

Rhodium(III) iodide, 99.9% (metals basis), Rh 20.8% min

Potassium aquapentachlororuthenate(III), Premion™, 99.99% (metals basis), Ru 26.4% min

4′-Fluoroisobutyrophenone, 97%

Hexachloroacetone, 99%

Myrcene, 90%, tech., stabilized

3-Oxetanol, 95%

4-n-Butoxybenzenesulfonyl chloride, 97%

Calcium carbonate, chelometric standard, ACS, 99.95-100.05%

Hexyl isocyanate, 99%

3-Bromobenzamide, 98+%

2-(4-Chlorophenyl)indole, 98%

Terbium(III,IV) oxide, REacton™, 99.9% (REO)

N-Phenyl-1-naphthylamine, 98%

2,3-Dichloro-5-(trifluoromethyl)pyridine, 97%

4-n-Heptyloxybenzaldehyde, 97%

Trichloroacetic anhydride, 95%

Gadolinium(III) carbonate hydrate, REacton™, 99.99% (REO)

Boron trifluoride diethyl etherate, 46.5% BF{3} min, packaged under Argon in resealable ChemSeal™ bottles

5,7-Dimethylisatin, 96%

Morpholine, ACS, 99.0% min

N-Benzyloxycarbonyl-L-aspartic acid 4-tert-butyl ester, 98%

Ytterbium(III) carbonate hydrate, REacton™, 99.9% (REO)

p-Toluenesulfinic acid sodium salt, 97% (dry wt.), water <5%

3,4-Difluoroanisole, 98%

2-Amino-4-methoxypyridine, 95%

Cadmium chloride, 98%, pure, anhydrous

Cyclohexene, 99% stab.

2-Benzyl-D-proline hydrochloride, 95%

2-Chlorophenylhydrazine hydrochloride, 97%

4-Iodobiphenyl, 97+%

2-Cyano-3-iodopyridine, 95%

1-Ethyl-1-methylpyrrolidinium bromide, 98%

Chromium(III) oxide, 99%

Naringin dihydrochalcone, 98%

4-Bromobutylboronic acid (1S,2S,3R,5S)-(+)-2,3-pinanediol ester, 95%

Anthracene, 99%

2-Bromo-5-methoxybenzonitrile, 98%

Silver nanoparticles, 80nm, 0.02 mg/ml, supplied in 2mM sodium citrate, 457nm absorption

EDTA disodium salt dihydrate, 99.0-101.0% (dried basis), crystals, USP, Multi-Compendial, GMP, J.T.Baker™

Indium(III) chloride, anhydrous, 98+%

Copper(II) sulfate pentahydrate, USP, Multi-Compendial, GMP, J.T.Baker™

Hexanoic anhydride, 97%

Nicotinuric acid, 98+%

Phthaloyl chloride, 94%

Potassium chloride, 0.0375M, Conductivity Standard

Instrument Calibration(ICAL) Standard, Solution A, Specpure™

1-Bromo-2,5-difluoro-4-nitrobenzene, 97%

Tin(IV) chloride hydrate, 98%

Acetic acid, ammonium salt, 98+%, for analysis

4-(4-Boc-1-piperazinylmethyl)benzeneboronic acid pinacol ester, 95%

3,4-Diaminoanisole dihydrochloride, 98%

beta,3-Dinitrostyrene, 98%

3-Methoxy-1,2-propanediol, 98%

(±)-Propylene oxide, 99.5%, extra pure, AcroSeal™

4-Chlororesorcinol, 98%

2-Amino-5-methyl-1,3,4-thiadiazole, 97%

Niobium(V) chloride, 99.95% (metals basis)

2-Acrylamido-2-methylpropanesulfonic acid, 98%

4-cis-Fluoro-L-prolinamide hydrochloride, 98%

6-Fluoroveratraldehyde, 97%

Trichloroacetyl isocyanate, 97%

trans-3-(Boc-amino)cyclohexanecarboxylic acid, 97%

3-Chloropropylamine hydrochloride, 98%

6-Methoxy-2-naphthylglyoxal hydrate, 98%, dry wt. basis

(S)-1-(2-Chlorophenyl)ethanol, 98%

2-Bromoaniline, 98%

Nickel(II) acetate tetrahydrate, 98+%

Zirconium wire, 1.0mm (0.04in) dia, 99.2% (metals basis excluding Hf), Hf 4.5% max

Amorolfine hydrochloride, 98%

Cyclohexane, 99.8%, for HPLC

Cyclopentylmagnesium bromide, 2.0M solution in diethyl ether, AcroSeal™

Tin(II) fluoride, 97.5%

1-Naphthylacetonitrile, 97%

Sodium borohydride, stable aq. soln., 4.4M in 14M NaOH

Gold(III) bromide, 99%

Lofexidine hydrochloride, 98+%

3,5-Dibromopyridine, 98+%

Scandium(III) bromide, ultra dry, 99.99% (metals basis)

Potassium indigotrisulfonate

Benzyltriethylammonium bromide, 98+%

Ethynylmagnesium chloride, 0.5M solution in THF/Toluene, AcroSeal™

Methylmalonic acid, 96%

Forchlorfenuron, 98%

Gallium(III) iodide, ultra dry, 99.999% (metals basis)

Thiosalicylic acid, 98%

N,N-Dimethylethanolamine, 99%

Iodomethane, 99%, stabilized

(S)-4-Cyano-4′-(2-methylbutyl)biphenyl, 97%

Tetrabutylammonium phosphate monobasic, 1M solution in ethanol, AcroSeal™

1,2-Dibromobenzene, 98%

Fullerene powder, 98+% C{70}

Chloroiodomethane, 98%, stab. with copper

1-Bromo-3-chloropropane, 99%

Urea, 98%, extra pure, pearls

Zirconium(IV) chloride, Reactor Grade, 99.5+% (metals basis)

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D: 8 Might 2013 Published: 16 May possibly 2013 References 1. Fabbri M, Croce CM, Calin GA

Stage vulval cells. (A92L9) Corresponding GFP fluorescence photomicrographs. (A2D

B, facilitating early carcinogenesis, invasion and migration in hepatocellular carcinoma[40, 41]. These

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Gckw/w mice, and was normalized by treatment with rosiglitazone or

Ys. Author manuscript; accessible in PMC 2015 December 01.Mehrotra et al.Pageand

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Aspase-3 activation inside the neurones (A and B). The therapies with

Andard artemisinin-based antimalarial drugs drastically threatens the malaria control campaign. This

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Timothy R. Fennell, Robert M. Lust,* Jared M. Brown, and Christopher

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Ow an increase, just by random variation. The purpose of the

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.13,17,18,56 Immune cells stimulated by TLR4 ligands evoke a spectrum of cellular

C/ EBP-/- tibiae compared with C/EBP+/+ tibiae (Fig. 5B

As marker for early detection, diagnosis, response prediction and monitoring, disease

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Sed this important problem employing the genetically tractable modelSubmitted December five, 2012, and

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Ts who necessary noninvasive respiratory care have been older and more comorbid

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Inhibits Melanogenesis by way of the PKA Signaling Pathway 2.3. Miglitol Inhibits Melanogenesis by way of

N-1-one linker as in 6a . The tested derivatives are classified

Or manage shRNA have been transplanted via tail vein injection. The expression

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YsoPC (16:0/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z)) (p = 0.0008), LysoPC (19:0/0:0) (p = 0.0036), LysoPC

To pressure stimuli which include chronic unpredictable mild anxiety and social

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Nearly all BT474 DTPs have been eradicated upon combination treatment, as evident

Amination, her vitals had been standard. Skin examination revealed diffuse thinning of

O-workers,41 where the redundancy on the coordinate method is identified and

Nterleukin-6 expression, but further study wants to be carried out to understand

Ental variables) [2]. Various research have already been performed to know the association

Tients when analyzing their survival. The recovered individuals present a statistically

Instruction models, Burgomaster et al.18, when comparing the effects of six

Peripheral blood along with the titer of polyclonal IgG should be evaluated

Rm of white precipwere characterized by X-ray diffraction (XRD), Fourier transform

Oefficients [44]. Figure 7 illustrates the influence of the changes in pH (from

Tal organs, as a result providing the infected particular person time for you to form enough

Mpairs coronavirus fusion and confers immune manage of viral illness. bioRxiv

PMFs, have already been identified as compounds having a high possible for

Ls as a result represent a conserved T cell population in humans, exhibit

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Nduced aseptic meningitis in a patient with acute lymphoblastic leukemia. Int

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Ody protected Tregs from NICD in vivo (Hubert et al., 2010). Interestingly

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T to categorize our circumstances using this revised classification. As infiltrating

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Ry phenotype. Anti-LAP treatment impacts tolerogenic CD103+ CD8 T cells We

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Uman agingCorresponding author: Mohammad Abdollahi. Division of Toxicology, Division of Toxicology and Pharmacology, Faculty of

Al Sciences, Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, Shizuoka, Japan K.

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Author: PDGFR inhibitor

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